Notícias médicas e pesquisa

Network meta-analysis of 716 double-blind RCTs with 159,362 participants found fewer AE-driven discontinuations with ARB-containing regimens, while CCBs, ACE inhibitor plus CCB, and beta-blocker plus thiazide increased withdrawals vs placebo.

Prospective cohort data suggest ~7 kg gain at 1 year and ~11 kg by 4 years, with 40–50% gaining at least 10%, and early 3-month gain tracking long-term trajectory—supporting risk stratification and proactive weight management.

Dose–response network meta-analysis of 64 RCTs with 5156 women found combined training best for fatigue and lean mass and resistance training best for function and strength, with benefits seen from as little as 10–40 minutes per week.

In a JAMA report using rapid ultraoxygenated recovery with extended preservation, 30-day survival reached 96% with 4% severe primary graft dysfunction, potentially easing adoption where normothermic regional perfusion is restricted.