Noticias médicas e investigación

Network meta-analysis of 716 double-blind RCTs with 159,362 participants found fewer AE-driven discontinuations with ARB-containing regimens, while CCBs, ACE inhibitor plus CCB, and beta-blocker plus thiazide increased withdrawals vs placebo.

A federal initiative has launched two proof-of-concept oncology trials plus an RFI for a summer pilot, aiming to reduce phase-to-phase delays by enabling FDA review of validated trial signals as data accrue.

Prospective cohort data suggest ~7 kg gain at 1 year and ~11 kg by 4 years, with 40–50% gaining at least 10%, and early 3-month gain tracking long-term trajectory—supporting risk stratification and proactive weight management.

Cluster crossover RCT in 23 US hospitals found Eat, Sleep, Console infants reached medical readiness 2.3 days sooner vs scheduled taper with no safety signal through 3 months, though 35% still required scheduled dosing.