A European Atherosclerosis Society consensus statement urges national childhood screening, revised diagnostic criteria, and earlier LDL-C goal–directed therapy, including treatment from age 6 when needed to prevent premature ASCVD.

In a population-based Ontario time-series of 5.3 million tests, weekly rates fell from 228.8 to 105.9 per 100,000 person-weeks during the first lockdown and remained below baseline through early 2022, with outpatient testing hit hardest and a modality shift toward more cardiac CT.

An ENTREQ-guided qualitative evidence synthesis of nine studies found clinicians generally support CRC and cervical screening guidance, but time pressure, poor EHR reminders, access delays and limited testing resources drive missed recommendations, especially in LMIC settings.

In a 3-hospital retrospective cohort of 1,576 Chinese adults, a back propagation neural network best predicted unplanned ICU transfer or reoperation with 77% sensitivity and 92% specificity in validation, with postoperative CT hematoma the top predictor.