MIPSS PlusLoading...Moderate Anemia (9-10.9 g/dL men, 8-9.9 g/dL women)No0Yes+1Severe anemia (< 9g/dl men, < 8 g/dl women)No0Yes+2Constitutional symptomsNo0Yes+2Circulating blasts ≥ 2%No0Yes+1Absence of CALR type 1-like mutationNo0Yes+2HMR categoryNo0Yes+2Two or more HMR mutationsNo0Yes+3Unfavorable karyotypeNo0Yes+3Very high-risk karyotypeNo0Yes+4IndikationenHinweise & Vorsichtsmaßnahmen