WHO Diagnostic Criteria for Polycythemia VeraLoading...Hgb > 16.5 g/dl in men or > 16.0 g/dl in women or hct > 49% in men or > 48% in womenNo0Yes+2Bone marrow biopsy showing age-adjusted hypercellularity with trilineage growth (panmyelosis), including prominent erythroid, granulocytic, and megakaryocytic proliferation, with pleomorphic, mature megakaryocytes (differences in size)No0Yes+2Presence of JAK2 V617F or JAK2 exon 12 mutationNo0Yes+1Subnormal serum erythropoietin level (< 2.6 mU/mL, reference value may vary by laboratory)No0Yes+1