Revised Ghent Nosology for Marfan Syndrome

Wrist and thumb sign

Wrist or thumb sign

Pectus carinatum deformity

Pectus excavatum or chest asymmetry

Hindfood deformity

Plain pes planus

Pneumothorax

Dural ectasia

Protrusio acetabuli

Reduced upper segment/lower segment ratio and increase arm span/height and no severe scoliosis

Scoliosis or thoracolumbar kyphosis

Reduced elbow extension (equal to 170 degrees with full extension)

At a minimum, 3 of the following 5 features: dolichocephaly, enophthalmos, down-slanting palpebral fissures, malar hypoplasia, retrognathia

Skin striae

Myopia greather than 3 diopters

Mitral valve prolapse