MASCC Risk Index for Febrile Neutropenia

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Burden of illness (symptom severity)

Hypotension (sBP < 90 mmHg)

Active COPD

Type of cancer

Dehydration requiring IV fluids

Status at onset of fever

Age (years)

References

B. Rangarajan. Rater.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2020
B. Zheng. Accuracy of the Multinational Association of Supportive Care in Cancer (MASCC) and Clinical Index of Stable Febrile Neutropenia (CISNE) scores for predicting serious complications in adult patients with febrile neutropenia: A systematic review and meta-analysis.. Critical reviews in oncology/hematology, 2020
R. Taplitz. Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018
A. Carmona-Bayonas. Prediction of serious complications in patients with seemingly stable febrile neutropenia: validation of the Clinical Index of Stable Febrile Neutropenia in a prospective cohort of patients from the FINITE study.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015
W. Kern. Oral antibiotics for fever in low-risk neutropenic patients with cancer: a double-blind, randomized, multicenter trial comparing single daily moxifloxacin with twice daily ciprofloxacin plus amoxicillin/clavulanic acid combination therapy--EORTC infectious diseases group trial XV.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013
C. Flowers. Antimicrobial prophylaxis and outpatient management of fever and neutropenia in adults treated for malignancy: American Society of Clinical Oncology clinical practice guideline.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013
O Teuffel. Outpatient management of cancer patients with febrile neutropenia: a systematic review and meta-analysis.. Annals of oncology : official journal of the European Society for Medical Oncology, 2011
J. Klastersky. The Multinational Association for Supportive Care in Cancer risk index: A multinational scoring system for identifying low-risk febrile neutropenic cancer patients.. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000