International Prognostic Score for Asymptomatic Early-stage CLL (IPS-E)

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Unmutated IGHV genes

Absolute lymphocyte count > 15×10^9/L

Palpable lymph nodes

References

Miguel Arguello-Tomas. Risk scores predicting disease progression in early-stage CLL: Comparative analysis and usefulness of IGHV subset #2 to improve their accuracy.. Cancer, 2024
S. Alshemmari. Evaluation of the CLL-IPI and IPS-E Prognostic Indices in a Young Middle Eastern Population with Chronic Lymphocytic Leukemia: A Retrospective Analysis at the Kuwait Cancer Control Center. Medical Principles and Practice, 2023
Adalgisa Condoluci. International prognostic score for asymptomatic early-stage chronic lymphocytic leukemia.. Blood, 2020
B Eichhorst. Chronic lymphocytic leukaemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.. Annals of oncology : official journal of the European Society for Medical Oncology, 2020
L. Smolej. External validation of International Prognostic Score for asymptomatic early stage chronic lymphocytic leukaemia and proposal of an alternative score. British Journal of Haematology, 2020