4C Mortality Score for COVID-19

Score of 9 or more is high risk

Age (in years)

Sex

Glasgow Coma Score

C reactive protein

No of comorbidities

Respiratory rate

Urea

Peripheral oxygen saturation on room air

References

Anum Zahra. Is frailty incremental to the 4C Mortality model for mortality risk prediction in hospitalized older individuals with COVID-19 disease?. Journal of clinical epidemiology, 2025
Adarsh Bhimraj. Infectious Diseases Society of America Guidelines on the Treatment and Management of Patients With COVID-19 (September 2022).. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024
Katharina S Appel. A Systematic Review of Predictor Composition, Outcomes, Risk of Bias, and Validation of COVID-19 Prognostic Scores.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024
V. M. de Jong. Clinical prediction models for mortality in patients with covid-19: external validation and individual participant data meta-analysis. The BMJ, 2022
Stephen R Knight. Prospective validation of the 4C prognostic models for adults hospitalised with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol.. Thorax, 2022
Sean Wei Xiang Ong. Validation of ISARIC 4C Mortality and Deterioration Scores in a Mixed Vaccination Status Cohort of Hospitalized Coronavirus Disease 2019 (COVID-19) Patients in Singapore.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022
Stephen R Knight. Risk stratification of patients admitted to hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: development and validation of the 4C Mortality Score.. BMJ (Clinical research ed.), 2020