IV, Alteplase

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References

  1. Craig S Anderson. Safety and efficacy of low-intensity versus standard monitoring following intravenous thrombolytic treatment in patients with acute ischaemic stroke (OPTIMISTmain): an international, pragmatic, stepped-wedge, cluster-randomised, controlled non-inferiority trial.. Lancet (London, England), 2025
  2. Charles B Majoie. Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials.. Lancet (London, England), 2023
  3. Katherine T. Mun. Fragility Index Meta-Analysis of Randomized Controlled Trials Shows Highly Robust Evidential Strength for Benefit of <3 Hour Intravenous Alteplase. Stroke, 2022
  4. S. Mendelson. Diagnosis and Management of Transient Ischemic Attack and Acute Ischemic Stroke: A Review.. JAMA, 2021
  5. G. Thomalla. Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging: systematic review and meta-analysis of individual patient data.. Lancet, 2020
  6. Pengfei Yang. Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke.. The New England journal of medicine, 2020
  7. B. Campbell. Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a systematic review and meta-analysis of individual patient data. The Lancet, 2019
  8. A. Kelly. Guideline: The AHA/ASA made 217 recommendations for early management of acute ischemic stroke in adults. Annals of Internal Medicine, 2018
  9. Lucas McCarthy. Pooled RCTs: In patients with acute ischemic stroke, alteplase increases intracerebral hemorrhage. Annals of Internal Medicine, 2016
  10. William N Whiteley. Risk of intracerebral haemorrhage with alteplase after acute ischaemic stroke: a secondary analysis of an individual patient data meta-analysis.. The Lancet. Neurology, 2016
  11. Jonathan Emberson. Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials.. Lancet (London, England), 2014
  12. Joanna M Wardlaw. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis.. Lancet (London, England), 2012